Chaparral Labs · Multi-disease KB
Knowledge Platform
A multi-omics knowledge graph for therapeutics. Disease-scoped, source-grounded, and built for the LLM era.
LLM-ready APISource-groundedOpen OpenAPI
Entities
2032
Proteins
2008
Papers
24
Sources
2
UniProt · SFARI
Recently ingested
latest 12- 31398340Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks.
- 30564305Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model.
- 28263302Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.
- 30804558Identification of common genetic risk variants for autism spectrum disorder.
- 25363760Synaptic, transcriptional and chromatin genes disrupted in autism.
- 31981491Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
- 32572268Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
- 31926610Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.
- 27989508A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.
- 35115731Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
- ABAT4-aminobutyrate aminotransferase, mitochondrial
- AACSAcetoacetyl-CoA synthetase
Data sources
- UniProt
Reviewed Swiss-Prot proteins, function & disease annotations.
- SFARI Gene
Curated ASD risk genes (Category 1 + Syndromic).