Neurexin-2-beta

# Neurexin-2-beta Summary

Neurexin-2-beta is a neuronal cell surface protein encoded by the NRXN2 gene (UniProt: P58401). It functions in cell recognition and cell adhesion processes, serving as a membrane-bound mediator of intercellular interactions in the nervous system.

As a neurexin family member, this protein operates within synaptic and neuronal development pathways where it participates in establishing and maintaining cellular contacts. The protein's role in cell adhesion mechanisms positions it within broader neural development and connectivity networks.

Neurexin-2-beta is classified as SFARI Category 2 (SFARI Cat 2), indicating it is considered a candidate gene with evidence suggesting involvement in autism spectrum disorder. This classification reflects its potential relevance to neurodevelopmental disorder etiology, though definitive mechanistic links require further investigation.