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Publication

Endolysosome and autophagy dysfunction in Alzheimer disease.

Hung Christy, Livesey Frederick J

disease:ad

Abstract

Abnormalities of the neuronal endolysosome and macroautophagy/autophagy system are an early and prominent feature of Alzheimer disease (AD).

MeSH Terms

Alzheimer DiseaseAutophagyCRISPR-Associated Protein 9CRISPR-Cas SystemsGene EditingHumansLDL-Receptor Related ProteinsLysosomesMembrane Transport ProteinsNeurons